Your base in Factorio can get very big and complex after some time, and not everything works properly all the time. Your certain buildings can stop working due to limitations and halt the functioning of your whole system. Also, if you having difficulties finding a certain ore, you can adjust it to spawn more frequently. Resources that are further away from your base will be richer, so you will have to build more logistics to supply your base. Resource Spawner Overhaul is a great Factorio mod that reworks the in-game resource spawning system to be region based.
FARL mod places rails, signals, electric poles, removes trees, rocks that are in the way and places a new layout on the maintenance mode, making things much faster and smoother. Factorio gives you many choices in regards to gameplay, and if you choose to use trains a lot, this is an essential mod for you.